Hyperscape: visualization for complex biological networks.
Identifieur interne : 000694 ( Main/Exploration ); précédent : 000693; suivant : 000695Hyperscape: visualization for complex biological networks.
Auteurs : Graham L. Cromar [Canada] ; Anthony Zhao [Canada] ; Alex Yang ; John Parkinson [Canada]Source :
- Bioinformatics (Oxford, England) [ 1367-4811 ] ; 2015.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Chromatin.
- metabolism : Elastic Tissue.
- Computer Graphics, Software, Systems Biology.
Abstract
Network biology has emerged as a powerful tool to uncover the organizational properties of living systems through the application of graph theoretic approaches. However, due to limitations in underlying data models and visualization software, knowledge relating to large molecular assemblies and biologically active fragments is poorly represented.
DOI: 10.1093/bioinformatics/btv385
PubMed: 26108529
Affiliations:
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Le document en format XML
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Cromar</name><affiliation wicri:level="1"><nlm:affiliation>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4</wicri:regionArea><wicri:noRegion>M5G 0A4</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Anthony" sort="Zhao, Anthony" uniqKey="Zhao A" first="Anthony" last="Zhao">Anthony Zhao</name><affiliation wicri:level="1"><nlm:affiliation>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4</wicri:regionArea><wicri:noRegion>M5G 0A4</wicri:noRegion></affiliation></author><author><name sortKey="Yang, Alex" sort="Yang, Alex" uniqKey="Yang A" first="Alex" last="Yang">Alex Yang</name><affiliation><nlm:affiliation>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4, Canada, Department of Biochemistry and.</nlm:affiliation><wicri:noCountry code="subField">Department of Biochemistry and</wicri:noCountry></affiliation></author><author><name sortKey="Parkinson, John" sort="Parkinson, John" uniqKey="Parkinson J" first="John" last="Parkinson">John Parkinson</name><affiliation wicri:level="4"><nlm:affiliation>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4, Canada, Department of Biochemistry and Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4, Canada, Department of Biochemistry and Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26108529</idno><idno type="pmid">26108529</idno><idno type="doi">10.1093/bioinformatics/btv385</idno><idno type="wicri:Area/PubMed/Corpus">000384</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000384</idno><idno type="wicri:Area/PubMed/Curation">000384</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000384</idno><idno type="wicri:Area/PubMed/Checkpoint">000384</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000384</idno><idno type="wicri:Area/Ncbi/Merge">001C16</idno><idno type="wicri:Area/Ncbi/Curation">001C16</idno><idno type="wicri:Area/Ncbi/Checkpoint">001C16</idno><idno type="wicri:Area/Main/Merge">000695</idno><idno type="wicri:Area/Main/Curation">000694</idno><idno type="wicri:Area/Main/Exploration">000694</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Hyperscape: visualization for complex biological networks.</title><author><name sortKey="Cromar, Graham L" sort="Cromar, Graham L" uniqKey="Cromar G" first="Graham L" last="Cromar">Graham L. Cromar</name><affiliation wicri:level="1"><nlm:affiliation>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4</wicri:regionArea><wicri:noRegion>M5G 0A4</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Anthony" sort="Zhao, Anthony" uniqKey="Zhao A" first="Anthony" last="Zhao">Anthony Zhao</name><affiliation wicri:level="1"><nlm:affiliation>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4</wicri:regionArea><wicri:noRegion>M5G 0A4</wicri:noRegion></affiliation></author><author><name sortKey="Yang, Alex" sort="Yang, Alex" uniqKey="Yang A" first="Alex" last="Yang">Alex Yang</name><affiliation><nlm:affiliation>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4, Canada, Department of Biochemistry and.</nlm:affiliation><wicri:noCountry code="subField">Department of Biochemistry and</wicri:noCountry></affiliation></author><author><name sortKey="Parkinson, John" sort="Parkinson, John" uniqKey="Parkinson J" first="John" last="Parkinson">John Parkinson</name><affiliation wicri:level="4"><nlm:affiliation>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4, Canada, Department of Biochemistry and Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Program in Molecular Structure and Function, Hospital for Sick Children, 21-9830 PGCRL, 686 Bay Street, Toronto, ON, M5G 0A4, Canada, Department of Biochemistry and Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author></analytic><series><title level="j">Bioinformatics (Oxford, England)</title><idno type="eISSN">1367-4811</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Chromatin (metabolism)</term><term>Computer Graphics</term><term>Elastic Tissue (metabolism)</term><term>Software</term><term>Systems Biology</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Chromatin</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Elastic Tissue</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Computer Graphics</term><term>Software</term><term>Systems Biology</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Network biology has emerged as a powerful tool to uncover the organizational properties of living systems through the application of graph theoretic approaches. However, due to limitations in underlying data models and visualization software, knowledge relating to large molecular assemblies and biologically active fragments is poorly represented.</div></front></TEI><affiliations><list><country><li>Canada</li></country><region><li>Ontario</li></region><settlement><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><noCountry><name sortKey="Yang, Alex" sort="Yang, Alex" uniqKey="Yang A" first="Alex" last="Yang">Alex Yang</name></noCountry><country name="Canada"><noRegion><name sortKey="Cromar, Graham L" sort="Cromar, Graham L" uniqKey="Cromar G" first="Graham L" last="Cromar">Graham L. Cromar</name></noRegion><name sortKey="Parkinson, John" sort="Parkinson, John" uniqKey="Parkinson J" first="John" last="Parkinson">John Parkinson</name><name sortKey="Zhao, Anthony" sort="Zhao, Anthony" uniqKey="Zhao A" first="Anthony" last="Zhao">Anthony Zhao</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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